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Master Organic Chemistry Reaction Guide

SN2 reaction of amines with alkyl chlorides to give ammonium salts

Description: Amines will react with alkyl halides to give ammonium salts. Importantly, this occurs even if only one equivalent of the alkyl halide and amine are used.

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Real-Life Examples:

Org. Synth. 1928, 8, 38

DOI Link:10.15227/orgsyn.008.0038

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Org. Synth. 1932, 12, 40

DOI Link:10.15227/orgsyn.012.0040

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Org. Synth. 1932, 12, 40

DOI Link: 10.15227/orgsyn.012.0040

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Org. Synth. 1939, 19, 61

DOI Link: 10.15227/orgsyn.019.0061

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Org. Synth. 1938, 18, 56

DOI Link: 10.15227/orgsyn.018.0056

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4 thoughts on “SN2 reaction of amines with alkyl chlorides to give ammonium salts

  1. Hi, in Description is written “+ salt”. What kind of salt is created? I suppose that there is 2 HX? Thx, P.

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