Comments for Master Organic Chemistry

Comment on Degrees of Unsaturation (or IHD, Index of Hydrogen Deficiency) by Apurva

Apurva — Sat, 21 Sep 2024 03:46:33 +0000

I read that in Dewar benzene, the middle C1-C4 linkage in not sigma bond but 2p-2p pi bond (special type of pi without sigma).

Comment on Formation of Cyanohydrins from ketones and aldehydes by James Ashenhurst

James Ashenhurst — Thu, 19 Sep 2024 18:29:38 +0000

In reply to Amani Araji. Uh oh, looks like that belongs in alkyne formation, not cyanohydrin formation. Will remove. Thank you!

Comment on Formation of cyclopropanes from alkenes using methylene carbene (:CH2) by James Ashenhurst

James Ashenhurst — Wed, 18 Sep 2024 21:40:05 +0000

In reply to NATHAN ILIUC. Woops! That's a typo. Should have the chloros attached. Will fix.

Comment on Diels-Alder Reaction: Kinetic and Thermodynamic Control by Yonas

Yonas — Wed, 18 Sep 2024 18:07:37 +0000

Thank you

Comment on Formation of cyclopropanes from alkenes using methylene carbene (:CH2) by NATHAN ILIUC

NATHAN ILIUC — Wed, 18 Sep 2024 06:00:57 +0000

Hello, for the 3rd to last flashcard on this page, from what I observe, the reagents CHCl3 and KOt-Bu are used to stimulate Dihalocyclopropanation involving an alkene. If that is true, why doesn’t the epoxide ring in this case contain 2 chlorines attached to a carbon in the final product? What makes the 2nd to last flashcard have chlorine atoms attached to the carbon on the epoxide ring instead? Thanks.

Comment on Formation of Cyanohydrins from ketones and aldehydes by Amani Araji

Amani Araji — Tue, 17 Sep 2024 16:30:15 +0000

Hello,
Can you explain The First Quiz Card

Comment on Reactions of Dienes: 1,2 and 1,4 Addition by PMT help-Tips to learn organic chemistry. – Sriharsha Koduru

PMT help-Tips to learn organic chemistry. – Sriharsha Koduru — Mon, 16 Sep 2024 13:20:16 +0000

[…] are two posts on 1,2 and 1,4 additions of acids dienes:part 1 and part […]

Comment on The 4 Major Classes of Reactions in Org 1 by Vinaya

Vinaya — Fri, 13 Sep 2024 16:39:35 +0000

Thank you !

Comment on Lewis Structures by Bismuth

Bismuth — Thu, 12 Sep 2024 21:49:36 +0000

the sense of humour used in these lessons and how fun they teach are what I love about this site

Comment on Reagent Friday: Lithium Di-isopropyl Amide (LDA) by James Ashenhurst

James Ashenhurst — Thu, 12 Sep 2024 17:21:30 +0000

In reply to Moses Alege.

LDA will not attach, but it may be strong enough to form an aryne. For example one could deprotonate C-H and elimination of the best leaving group (Cl) would give an aryne, which could then undergo attack by a nucleophile. When the nucleophile does attack, it will likely do so such that the negative charge is placed closer to the electron withdrawing fluoro groups.
See this artice on arynes – possibly helpful. https://www.masterorganicchemistry.com/2018/09/17/nucleophilic-aromatic-substitution-2-benzyne/