Comments on: Nucleophilic Aromatic Substitution (2) – The Benzyne Mechanism https://www.masterorganicchemistry.com/2018/09/17/nucleophilic-aromatic-substitution-2-benzyne/ Sat, 13 Jan 2024 07:33:43 +0000 hourly 1 https://wordpress.org/?v=6.6.2 By: Hina https://www.masterorganicchemistry.com/2018/09/17/nucleophilic-aromatic-substitution-2-benzyne/#comment-682293 Sat, 13 Jan 2024 07:33:43 +0000 https://www.masterorganicchemistry.com/?p=11863#comment-682293 How protic and aprotic solvent effect benzyne formation. (Brief explanation needed)

]]> By: James Ashenhurst https://www.masterorganicchemistry.com/2018/09/17/nucleophilic-aromatic-substitution-2-benzyne/#comment-653780 Sun, 30 Apr 2023 23:49:32 +0000 https://www.masterorganicchemistry.com/?p=11863#comment-653780 In reply to RUPANKITA MUKHERJEE.

Thank you

]]> By: RUPANKITA MUKHERJEE https://www.masterorganicchemistry.com/2018/09/17/nucleophilic-aromatic-substitution-2-benzyne/#comment-653750 Sun, 30 Apr 2023 15:26:00 +0000 https://www.masterorganicchemistry.com/?p=11863#comment-653750 🙏]]> So wellexplained and helpful! Your clear and lucid language really helps me a lot in understanding many important topics. Whenever I look for doubt clearance with respect to organic chemistry and I find your post, I know they’re gonna be well looked after. With tons of thanks, from India.🙏🙏

]]> By: Amen Bibi https://www.masterorganicchemistry.com/2018/09/17/nucleophilic-aromatic-substitution-2-benzyne/#comment-649929 Sat, 11 Mar 2023 08:28:33 +0000 https://www.masterorganicchemistry.com/?p=11863#comment-649929 Thankyou so much. All content in this website is very informative

]]> By: Ashif Hussain https://www.masterorganicchemistry.com/2018/09/17/nucleophilic-aromatic-substitution-2-benzyne/#comment-649731 Wed, 08 Mar 2023 15:54:35 +0000 https://www.masterorganicchemistry.com/?p=11863#comment-649731 Thank you sir.It helps me to understand this concept which is very important for indian competitive exams.

]]> By: Shweta https://www.masterorganicchemistry.com/2018/09/17/nucleophilic-aromatic-substitution-2-benzyne/#comment-643398 Tue, 29 Nov 2022 12:28:30 +0000 https://www.masterorganicchemistry.com/?p=11863#comment-643398 ]]> Excellent ..the way you divided & explained the concept🤩

]]> By: James Ashenhurst https://www.masterorganicchemistry.com/2018/09/17/nucleophilic-aromatic-substitution-2-benzyne/#comment-635593 Thu, 18 Aug 2022 14:46:36 +0000 https://www.masterorganicchemistry.com/?p=11863#comment-635593 In reply to Abhyuday Krishna.

No, rate determining step is formation of the aryne (deprotonation). The attack is fast.

]]> By: Chizzy Best https://www.masterorganicchemistry.com/2018/09/17/nucleophilic-aromatic-substitution-2-benzyne/#comment-619977 Mon, 07 Feb 2022 22:03:54 +0000 https://www.masterorganicchemistry.com/?p=11863#comment-619977 ☺]]> Well done for the teaching☺☺

]]> By: James Ashenhurst https://www.masterorganicchemistry.com/2018/09/17/nucleophilic-aromatic-substitution-2-benzyne/#comment-601091 Tue, 18 May 2021 19:08:17 +0000 https://www.masterorganicchemistry.com/?p=11863#comment-601091 In reply to Pranav.

Look for the presence of strong base (NaNH2) in the case of aryne formation.

]]> By: Pranav https://www.masterorganicchemistry.com/2018/09/17/nucleophilic-aromatic-substitution-2-benzyne/#comment-601030 Sun, 16 May 2021 12:41:55 +0000 https://www.masterorganicchemistry.com/?p=11863#comment-601030 Informative post.. just a quick question… how do we decide if a reaction proceeds in the normal Addition Elimination Mechanism or the Benzyne Mechanism.. any parameters like temperature/reagent, etc?

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