Comments on: Electrophilic Aromatic Substitutions (1) – Halogenation of Benzene

By: ベンゼンのハロゲン化 – 30歳からの進路選択

ベンゼンのハロゲン化 – 30歳からの進路選択 — Sat, 29 Jun 2024 03:34:25 +0000

[…] 出典：https://www.masterorganicchemistry.com/2018/04/18/electrophilic-aromatic-substitutions-1-halogenatio… […]

By: James Ashenhurst

James Ashenhurst — Thu, 19 May 2022 19:55:18 +0000

In reply to Rajnikant. This would have to involve a phenyl radical intermediate. Phenyl radicals are known, and they can be made from (for example) aryl halides with reductants like tributyl tin hydride.

By: Rajnikant

Rajnikant — Wed, 18 May 2022 03:58:58 +0000

Can free radical substitution take pace on benzene?

By: Halogenation of Benzene and other Aromatics - npodu

Halogenation of Benzene and other Aromatics - npodu — Fri, 19 Mar 2021 11:30:37 +0000

[…] Chlorination and bromination occurs at normal conditions while fluorination is so much fast and exhaustive that it can break all the bonds and iodination is so slow that it is reversible.People also search about: Reactions of Aromatic Molecules: […]

By: James Ashenhurst

James Ashenhurst — Wed, 06 May 2020 02:27:01 +0000

In reply to Tal Parness. Any of the eight C-H bonds can undergo electrophilic aromatic substitution. Your task is to show that this results in only two distinct compounds.

By: Tal Parness

Tal Parness — Tue, 05 May 2020 19:10:59 +0000

how come naphthalene only has 2 derivatives? Shouldn’t there be a derivative on all the sp2 carbons?

By: Waseeq Ur Rehman

Waseeq Ur Rehman — Tue, 04 Feb 2020 14:31:23 +0000

useful material. Well done, thanks

By: Andrea

Andrea — Fri, 06 Dec 2019 08:20:14 +0000

Hi James! In this case if I use two equivalents of chlorine will I get a disubstituted benzene? Thanks

By: James

James — Tue, 23 Oct 2018 19:01:23 +0000

In reply to Evan.

One phenyl group is attached to a carbonyl (C=O). The other is attached to a CH2 attached to a carbonyl.

Which phenyl group is more activated? : – )

By: Evan

Evan — Thu, 28 Jun 2018 09:08:26 +0000

Hello, love the articles. I am studying for a test including this topic, was wondering where would the Bromine attack if there was a phenyl group attached to a ketone attached to a methyl group attached to another phenyl group. I believe it attaches to the phenyl group furthest from the ketone but was not sure.