Comments on: Acetylides from Alkynes, And Substitution Reactions of Acetylides

By: Good life

Good life — Sun, 07 Apr 2024 04:47:00 +0000

Can you prepare 3_chloro_4_methyl_2_hexyne from butyne In this way

By: James Ashenhurst

James Ashenhurst — Wed, 11 Nov 2020 18:08:32 +0000

In reply to Mia. Where have you read this? Acetylides will all be protonated by mineral acids.

By: Mia

Mia — Mon, 09 Nov 2020 15:54:48 +0000

Sir, I have read that sikver acetyllide and copper acetylide reacts with mineral acids to form alkynes whereas sodium acetylide donot ,why is that?

By: James Ashenhurst

James Ashenhurst — Thu, 05 Sep 2019 17:05:34 +0000

In reply to Hira Khalid. Protic solvents (pka about 14-18) are incompatible with acetylides (pKa about 25).

By: Hira Khalid

Hira Khalid — Mon, 02 Sep 2019 11:11:23 +0000

The solvent protic and a-protic also effect the product as in case protic we ll have more elimination pdt while in a-protic we ll get substitution products.
what is the best way to workout these reactions to get pure pdt?

By: James Ashenhurst

James Ashenhurst — Fri, 28 Jun 2019 19:41:10 +0000

In reply to Chinmay. Elimination. Acetylides are very strong bases and SN2 reactions don't happen at tertiary centers.

By: James Ashenhurst

James Ashenhurst — Sat, 27 Apr 2019 03:33:11 +0000

In reply to Lorik. Yes, exactly Lorik. Thank you

By: Chinmay

Chinmay — Wed, 31 Jan 2018 04:58:07 +0000

If we use tertiary alkylhalide,what will be the price the
Does it follow substitution or elimination?

By: Lorik

Lorik — Tue, 21 Nov 2017 15:20:13 +0000

In reply to Kumar Neelabh. Kumar, you only get elimination as the major product if you are reacting the acetylide ion with second and third degree alkyl halides.

By: Usama

Usama — Fri, 20 Jan 2017 13:50:55 +0000

In reply to Kumar Neelabh. yep, minor products do form but are essentially broken down or reacted to form further compounds